Yelwa, Armiya’u AhmedMainasara, Abdallah SuleimanAkuyam, Shehu AbubakarAdamu, Balarabe IsahUmar, Zayyanu UsmanAbubakar, Sharafudeen DahiruMuhammad, YahayaGamde, Solomon MatthiasAbdulazziz, Aisha2020-11-182020-11-182020-03Yelwa Armiya’u Ahmed, Mainasara Abdallah Suleiman, Akuyam Shehu Abubakar, Adamu Balarabe Isah, Umar Zayyanu Usman, Abubakar Sharafudeen Dahiru, Muhammad Yahaya, Gamde Solomon Matthias, Abdulazziz Aisha. Evaluation of serum sex hormones and CD4+ count among HIV patients on HAART, HAART naive patients and apparently healthy subjects in Sokoto, Nigeria. International Journal of Research in Medical Sciences. 2020 Mar; 8(3): 891-8952320-60712320-6012http://imsear.searo.who.int/handle/123456789/212155Background: Acquired Immunodeficiency Syndrome (AIDS) is a chronic disease associated with Human Immunodeficiency Virus (HIV) which progressively induces depletion of CD4+ T cells, and increased vulnerability to opportunistic infections. Previous reported studies associated HIV-infected men with sexual dysfunction; hypogonadism is the most common endocrinological disorders. Its prevalence remains poorly defined and widely ranging from different studies.Methods: This study evaluated a total of 135 serum sex hormones (testosterone, estrogen, follicle stimulating hormone and luteinizing hormone) and its correlation with CD4+ counts among HIV patients on HAART, HAART naïve patients and negative control subjects (n=45). CD4+ cell counts were estimated using standard flow cytometry method and serum sex hormones by competitive enzyme immunoassay technique.Results: There were significantly lower testosterone and CD4+ levels (p<0.05) among HIV positive HAART naïve men compared to negative control. LH and FSH indicated significant increased (p<0.05) among HIV positive men on HAART.Conclusions: Antiretroviral therapy improves sexual functions in males infected with human immunodeficiency virus. Hence, further study to evaluate its effects on other sexual behaviors.Acquired Immunodeficiency syndromeAntiretroviral therapyAntiretroviral naïve patientsSex hormonesEvaluation of serum sex hormones and CD4+ count among HIV patients on HAART, HAART naive patients and apparently healthy subjects in Sokoto, NigeriaJournal ArticleIndiaDepartment of Chemical Pathology, Usmanu Danfodiyo University Sokoto, NigeriaDepartment of Medical Laboratory Science, Ahmadu Bello University, Zaria, Kaduna State, NigeriaDepartment of Community Medicine, College of Health Sciences Usmanu Danfodiyo University Sokoto, NigeriaDepartment of Physiology, College of Health Sciences Usmanu Danfodiyo University Sokoto, NigeriaDepartment of Chemical Pathology, Rasheed Shekoni Teaching Hospital Dutse, Jigawa, NigeriaDepartment of Histopathology, College of Health Sciences, Usmanu Danfodiyo University, Sokoto State, Nigeria