Bunyaratavej, NKitimanon, NBoonthitikul, S2009-05-272009-05-272001-10-21Bunyaratavej N, Kitimanon N, Boonthitikul S. Study of the level of biochemical bone markers: NMID osteocalcin and bone resorptive marker (beta CTx) in Thai women. Journal of the Medical Association of Thailand. 2001 Oct; 84 Suppl 2(): S560-5http://imsear.searo.who.int/handle/123456789/43644Chotmaihet Thangphaet.Study of the level of NMID osteocalcin and Beta CTx in 700 Thai women. The mean of NMID osteocalcin = 21.45 SD = 11.18 95% CI = 20.12 to 22.79 ng/ml and betacrosslap = 0.445 ng/ml SD = 0.25 with 95% CI = 0.414 to 0.478 ng/ml in women who menopaused less than 10 years ago (n=237), these values were higher than in young adult females (n=63) and menstruating women (n=123) which was statistically significant (p=0.0001). The value of both bone markers in elderly women who had menopaused more than 10 years ago and were aged more than 60 years (n=94) showed a marked increase of NMID osteocalcin, 25.63 ng/ml SD = 14.22 ng/ml but the value of betacrosslap was below the young-menopausal women, 0.394 ng/ml SD = 0.241 ng/ml 95% CI = 0.344 to 0.444 ng/ml. Menopausal women are at a high risk of osteoporosis due to high bone turnover. In our study, the NMID osteocalcin had a high correlation with betacrosslap (r=0.789 p=0.0001) while both bone markers had a weak correlation with bone mass density of radius, lumbar spine and hip by DXA. (r=0.29 p=0.0001).engAdultAgedBiological Markers --bloodBone Resorption --diagnosisCollagen --bloodCollagen Type IFemaleHumansMenopause --bloodMiddle AgedOsteoporosis, Postmenopausal --diagnosisPeptide Fragments --bloodPeptides --bloodThailandJournal Article