Singh, JRavi, R NDutta, A KKumari, SKhare, S1992-11-012009-05-271992-11-012009-05-271992-11-01Singh J, Ravi RN, Dutta AK, Kumari S, Khare S. Immunogenicity of enhanced potency inactivated polio vaccine. Indian Pediatrics. 1992 Nov; 29(11): 1353-6http://imsear.searo.who.int/handle/123456789/12097Fifty two children were immunized with two doses of enhanced potency inactivated polio vaccine in order to determine its efficacy. The vaccine was very efficacious with 92.3, 92.3 and 88.3% of the children seroconverting to the three poliovirus types, respectively. The vaccine was equally efficacious whether the two doses were given at 4-week or 8-week intervals or when immunization was started at 6-7 weeks of age or later. The presence of maternal antibodies did not interfere significantly with the seroresponse to two doses of IPV-E. The study recommends that two doses of IPV-E give satisfactory seroconversion rates. Immunization can be started as early as 6 weeks age and the two doses can be given at 4 weeks interval to complete primary immunization against poliomyelitis.engAntibodies, Viral --bloodDose-Response Relationship, ImmunologicHumansImmunization ScheduleInfantPoliomyelitis --prevention & controlPoliovirus --immunologyPoliovirus Vaccine, Inactivated --immunologyJournal Article