Dadu, FahadKumar, SathishR., SadhanaM., Ram kumarKumar, Magesh2023-08-282023-08-282022-09Dadu Fahad, Kumar Sathish, R. Sadhana, M. Ram kumar, Kumar Magesh. An acute case of herpes zoster ophthalmicus with post-herpetic neuralgia and cranial nerve neuropathies. International Journal of Advances in Medicine. 2022 Sep; 9(9): 961-9632349-39332349-3925http://imsear.searo.who.int/handle/123456789/225875Herpes zoster is a common diagnosis in the emergency department which is caused by reactivation of varicella zoster virus (VZV). Reactivation in ophthalmic division of trigeminal nerve causes Herpes zoster ophthalmicus. It is associated with a rash in the distribution of the trigeminal nerve dermatomes especially in ophthalmic and maxillary divisions. The most often complications of HZO are episcleritis, keratitis, glaucoma, and cataracts. HZO with cranial neuropathy is a very rare condition. So herewith wereport a case 51years old female with swelling, redness in right eye and drooping of eyelids on the right side. She had tearing and double vision. She was diagnosed with herpes zoster ophthalmicus with neuropathy of 3rd,4thand 6th cranial nerves. The patient was treated and discharged in a healthy condition. Timely diagnosis and treatment can decrease morbidity and prevent the complication.Herpes zoster opthalmicusCranial nerve neuropathiesVaricella zostervirusJournal ArticleIndiaDepartment ofMedicine,SaveethaMedical Collegeand Hospital, Saveetha Nagar, Thandalam, Chennai, Tamil Nadu, India