Cardoso das, DSoares, C MAzevedo, M SLeite, J PMunford, VRácz, M L2000-06-032009-05-272000-06-032009-05-272000-06-03Cardoso das D, Soares CM, Azevedo MS, Leite JP, Munford V, Rácz ML. Serotypes and subgroups of rotavirus isolated from children in central Brazil. Journal of Health, Population, and Nutrition. 2000 Jun; 18(1): 39-43http://imsear.searo.who.int/handle/123456789/604Journal of Health, Population, and Nutrition.Group A rotavirus, obtained from children of Goiânia, Brazil, during 1987-1994, were analyzed for subgroup and G serotype by enzyme-linked immunosorbent assay with monoclonal antibodies. The index of serotyping obtained was 61.4% with the following proportions: G1--19.7%, G2--28.0%, G3--9.8%, G4--1.5%, and G5--2.3%. It was observed that G1 occurred from 1987 to 1989 and from 1993 to 1994, and G2 from 1990 to 1993. About 94% of the samples (85/90) could be subgrouped with the following results: 55.5% for SG II, 7.8% SG I, and 31.1% for SG non-I-non-II. Unusual relationship patterns were also detected among serotypes, subgroups, and profiles of electropherotypes in 57.0% of the samples: 20 of them were G2/SG II/"long" profile. The results suggest that variation in temporal and regional characteristics should be considered in the development of rotavirus vaccine.engAntibodies, Monoclonal --diagnostic useAntibodies, Viral --bloodBrazil --epidemiologyChildChild, PreschoolDiarrhea --epidemiologyEnzyme-Linked Immunosorbent AssayFeces --virologyFemaleHumansImmunization Programs --organization & administrationInfantMaleRotavirus --classificationRotavirus Infections --epidemiologySerotypingJournal Article