Shashikiran, N DKumar, N CSubba Reddy, V V2003-12-102009-06-022003-12-102009-06-022003-12-10Shashikiran ND, Kumar NC, Subba Reddy VV. Fluoride uptake by enamel and dentin from bonding agents and composite resins: a comparative study. Journal of the Indian Society of Pedodontics and Preventive Dentistry. 2003 Dec; 21(4): 125-30http://imsear.searo.who.int/handle/123456789/114725The present study was performed to compare the amount of in vitro fluoride uptake by enamel and dentin from fluoridated bonding agent with non-fluoridated composite (Group I), non-fluoridated bonding agent with fluoridated composite (Group II) and fluoridated bonding agent with fluoridated composite resin (Group III). Sixty extracted premolars were selected and divided into three groups of 20 teeth each. Restorative materials were applied according to manufacturer's instructions into standard windows created in the teeth, cured and placed in de-ionised water for three months. The fluoride content of successive acid etch biopsy was determined by specific ion-electrode analysis. Although significant amount of fluoride uptake occurred in all the test groups, fluoride uptake was found to be highly significant in dentin when compared to enamel in Group, I, II and III (P<0.001). The fluoride uptake was greater by both enamel and dentin in Group III ie fluoridated bonding agent with fluoridated composite resin.engAcid Etching, DentalAcrylic Resins --chemistryAnalysis of VarianceCariostatic Agents --chemistryComposite Resins --chemistryDental Enamel --metabolismDentin --metabolismDentin-Bonding Agents --chemistryFluorides --chemistryHumansIon-Selective ElectrodesMethacrylates --chemistryPolymethacrylic Acids --chemistryPolyurethanes --chemistryStatistics, NonparametricTime FactorsClinical Trial