Majumder, SMandal, S KChowdhury, S RoyBandyopadhyay, DBandyopadhyay, RChakraborty, P P2007-10-052009-05-312007-10-052009-05-312007-10-05Majumder S, Mandal SK, Chowdhury SR, Bandyopadhyay D, Bandyopadhyay R, Chakraborty PP. Scleredema of Buschke: a rare post-streptococcal complication. Journal of the Association of Physicians of India. 2007 Oct; 55(): 737-8http://imsear.searo.who.int/handle/123456789/94971A 19-year male presented with acute onset, gradually progressive symmetric indurations involving the skin over the face, neck, shoulders and upper part of chest following an upper respiratory tract infection. Detailed history and examination did not reveal evidence of Raynauds' phenomenon, nail changes, digital ulcers, pigmentation or any systemic involvement. Autoantibodies for systemic sclerosis were absent. Histopathology of skin biopsy documented scleredema. Antistreptolysin O (ASO) titer was elevated. We diagnosed a case of Scleredema adultorum of Buschke following a streptococcal throat infection. We report this case to highlight the importance of clinically differentiating this relatively benign, self-limiting disorder from systemic sclerosis.engAdultDiagnosis, DifferentialHumansMalePenicillins --therapeutic usePharynx --physiopathologyRisk FactorsScleredema Adultorum --drug therapyStreptococcal Infections --complicationsTime FactorsCase Reports