Mukherjee, ShuvankarDash, AnshumanTiwari, Shreekant2020-11-182020-11-182020-01Mukherjee Shuvankar, Dash Anshuman, Tiwari Shreekant. Seropositivity of Scrub Typhus Inpatients Attending a Tertiary Care Hospital in Western Odisha. Journal of Evolution of Medical and Dental Sciences. 2020 Jan; 9(4): 178-1812278-48022278-4748http://imsear.searo.who.int/handle/123456789/214993Scrub typhus is a vector borne Rickettsial disease caused by Orientia tsutsugamushi and has been reported from tsutsugamushi triangle which includes India. It is a re-emerging pathogen in India including the state of Odisha. This study was conducted to determine seropositivity of scrub typhus in patients attending a tertiary care hospital of Western Odisha.METHODSFifty febrile patients who were negative for Malaria, Dengue and Leptospira attending a tertiary care hospital of Western Odisha were enrolled in the study. 3 ml of blood was collected, and serum was separated. IgM SD Bioline Tsutsugamushi lateral flow immunochromatography test was performed as per manufacturer instruction. Positive samples were confirmed by PCR method (Geno-Sen’s ST Real Time PCR).RESULTS20% of patients were positive for IgM SD Bioline Tsutsugamushi card test. 60% of positive patients were male. 20% of positive patients were having pathognomonic eschar. 60 % of infected patients were in the age group of 10 - 30.CONCLUSIONSIn this study, 20% of febrile patients were positive for Scrub typhus infection. So, it should be included in the differential diagnosis of a febrile patient in Western Odisha.Scrub TyphusSeropositivityWestern OdishaCard Test.Journal ArticleIndiaDepartment of Microbiology, Hitech Medical College and Hospital, Rourkela, Odisha, IndiaDepartment of Microbiology, Hitech Medical College and Hospital, Rourkela, Odisha, IndiaDepartment of Microbiology, Hitech Medical College and Hospital, Rourkela, Odisha, India.