Manas, DSrinivas, S RJithendra, K D2015-12-102015-12-102009-10Manas D, Srinivas S R, Jithendra K D. Role of antibiotics in periodontal therapy. Bangladesh Journal of Medical Science. 2009; 8(4): 91-101.2223-47212076-0299http://imsear.searo.who.int/handle/123456789/167813Loeshe in 1976 propounded the ‘Specific Plaque Hypothesis’ and efforts have been done since, to formulate a periodontal treatment regimen based on targeting of specific microorganisms. Antibiotics have gained importance as an arsenal in the treatment of periodontitis. This review takes a concise view on the role of antibiotics in periodontics. This review puts importance of antibiotics in a nutshell as a quick reference for the general practitioners in treating periodontal diseases. The selection and indication for the use of antibiotics is given with a note on resistanceenPeriodontitisantibioticsArticle