Anuroj, KPathmanand, CSueblinvong, VThisyakorn, CChotivitayatarakorn, P2009-05-272009-05-271997-06-01Anuroj K, Pathmanand C, Sueblinvong V, Thisyakorn C, Chotivitayatarakorn P. Ventricular functions in children with human immunodeficiency virus infection after ACE-inhibitors. The Southeast Asian Journal of Tropical Medicine and Public Health. 1997 Jun; 28(2): 375-9http://imsear.searo.who.int/handle/123456789/36258The Southeast Asian Journal of Tropical Medicine and Public Health.Nine pediatric symptomatic patients infected with human immunodeficiency virus with elevated pulmonary arterial pressure (MPA pressure) and ejection fraction (EF); and with fractional shortening, (FS) mean velocity of circumferential fiber shortening (MVCfc) and left ventricular peak systolic wall stress (PS) were prospectively evaluated using 2-dimensional and M-mode serial echocardiography and Doppler cardiography after administration of an ACE inhibitor (Inhibace 0.025 mg/kg/D orally) for 12 weeks. The MPA pressure was not decreased, however the MVCfc and PS improved significantly (p < 0.05). Further, long term evaluation is required to determine its effect in preventing dilated cardiomyopathy and elevated mean pulmonary pressure.engAngiotensin-Converting Enzyme Inhibitors --therapeutic useCardiomyopathy, Dilated --prevention & controlChild, PreschoolCilazapril --therapeutic useFemaleHIV Infections --complicationsHemodynamicsHumansHypertension, Pulmonary --drug therapyInfantMaleProspective StudiesStatistics, NonparametricVentricular Dysfunction --drug therapyClinical Trial