Kausar, SofiaAbbas, Muhammad ArshadAhmad, HajraYousef, NaziaAhmed, ZaheerHumayun, NaheedAshfaq, HiraHumayun, Ayesha2020-09-242020-09-242019-02Kausar Sofia, Abbas Muhammad Arshad, Ahmad Hajra, Yousef Nazia, Ahmed Zaheer, Humayun Naheed, Ashfaq Hira, Humayun Ayesha. Effect of Apple Cider Vinegar in Type 2 Diabetic Patients with Poor Glycemic Control: A Randomized Placebo Controlled Design. International Journal of Medical Research & Health Sciences. 2019 Feb; 8(2): 149-1592319-5886http://imsear.searo.who.int/handle/123456789/204994Aim: The aim of the trial was to measure the effect of apple cider vinegar on glycemic control and biochemical parameters in type 2 diabetes mellitus (DM) patients with poor glycemic control. Methods: A single-blind, randomized, placebo-controlled trial was conducted on 110 eligible types 2 DM patients who were selected and allocated into 2 groups. The interventional group was given 15 ml apple cider vinegar in 200 ml water during dinner for 3 months while the other group was placebo. Before and after HbA1C (glycosylated hemoglobin), fasting lipid profile, fasting blood sugar, anthropometrics, and dietary changes were assessed and analyzed using IBM SPSS version 20, through statistical tests. Formal ethical approval was obtained from the local institutional review board. Results: Significant mean change was found in interventional group in HbA1c (p<0.001), blood sugar fasting (p<0.001), total cholesterol (p=0.002), triglyceride (p=0.002) and hip-waist ratio (p=0.002). No significant change was observed in the mean of these statistics in the placebo group. No significant change was observed in height, weight, mid-upper arm ratio, and low density lipoprotein, high density lipoprotein and food frequency in intervention and placebo groups before and after. Conclusion: Apple cider vinegar if used regularly is effective in controlling diabetes, lowering hypercholesterolemia and hypertriglyceridemia in DM type 2 patients.VinegarDiabetesHyperglycemiaHypercholesterolemiaNutraceuticalJournal ArticleIndiaDepartment of Liver Transplant Unit, Shaikh Zayed Hospital Medical Complex, Lahore, PakistanDepartment of General Surgery, Ameer Udin Medical College/PGMI, Lahore General Hospital Lahore, PakistanDepartment of Environmental Design, Health and Nutritional Sciences, Allama Iqbal Open University, Islamabad, PakistanShalamar Institute of Health Sciences, Lahore, PakistanFMH College of Medicine and Dentistry, Lahore, PakistanAkhtar Saeed Medical and Dental College, Lahore, PakistanDepartment of Public Health and Community Medicine, Shaikh Khalifa Bin Zayed Al-Nahyan Medical College and Shaikh Zayed Postgraduate Medical Institute, Shaikh Zayed Medical Complex, Lahore, Pakistan