Aryadevi, C. P.Pradeep, GeethikaBhargavan, P. V.P. V., Shiji2023-08-282023-08-282022-12Aryadevi C. P., Pradeep Geethika, Bhargavan P. V., P. V. Shiji. Neuromyelitis optica presenting as neurogenic bladder. International Journal of Advances in Medicine. 2022 Dec; 9(12): 1224-12272349-39332349-3925http://imsear.searo.who.int/handle/123456789/225938Neuromyelitis optica(NMO) is an immune mediated disease of central nervous system primarily affecting optic nerves, spinal cord and brain stem. This case report describes a 24-year-old male with no comorbidities presented with high grade fever followed by proximal lower limbweakness and bilateral hydrouretero nephrosis without any lower urinary tract obstruction. He had clinical features of conus-cauda lesion with MRI spine showing features of longitudinally extensive transverse myelitis (LETM) and brain MRI showing involvement of splenium of corpus callosum. He improved with steroid therapy with in a period of 2 weeks and oral steroid was tapered of and stopped within a period of two months. There wasno relapse of symptoms so far.Neuromyelitis opticaNeurogenic bladderLower limb weaknessJournal ArticleIndiaDepartment of Medicine, Baby Memorial Hospital, Kozhikode, Kerala, IndiaDepartment of Medicine, Govt. Medical College, Kozhikode, Kerala, India