Singh, SaurabhKumar, ParaagChawla, Gurpreet KaurGupta, MeenuKusum, Anuradha2023-07-212023-07-212022-02Singh Saurabh, Kumar Paraag, Chawla Gurpreet Kaur, Gupta Meenu, Kusum Anuradha. Clinical profile of patients with esophageal carcinoma: A multicentric study from North India. Annals of International Medical and Dental Research. 2022 Feb; 8(1): 124-1312395-28222395-2814http://imsear.searo.who.int/handle/123456789/219900Background: Carcinoma esophagus is the 6th most common cancer in India with an incidence of 5.04% It most commonly affects older age individuals, with incidence peaking in seventh and eighth decades of life. Adenocarcinoma (AC) and Squamous cell carcinoma (SCC) are the two main histological variants. Our aim was to study the risk factors, clinical and epidemiological profile of patients diagnosed with Esophageal Cancer from two tertiary care centres located in North India.Methods:This was a retrospective study carried in departments of gastroenterology of two tertiary care hospitals North India. Data was collected from respective institutes for the previous 1 year i.e. from 1st October 2020 to 30th September 2021. All patients presenting to Gastroenterology OPD or emergency with dysphagia who were diagnosed as having Carcinoma esophagus were included in the study.Results:A total of 106 patients were included in this study. There were 44 females & 66 males. The most common presenting complaint was Dysphagia (48%) followed by Loss of weight (26.4%), Vomiting (in 23.6%) and Odynophagia (22.6%). Involvement of the lower one third of the oesophagus was the most common (37.7%). SCC (Squamous Cell Carcinoma) was the most common type of oesophageal carcinoma in this study, seen approximately in 80% of cases.Conclusion:Our study from North India suggested poor oral hygiene as a strong risk for carcinoma esophagus Males were more commonly affected and SCC was the predominant variant.Carcinoma esophagusAdenocarcinomaSquamous Cell Carcinoma.Journal ArticleIndiaAssistant Professor, Department of Gastroenterology, Himalyan Institute of Medical Sciences, Jolly Grant, Dehradun, Uttarakhand, India. Email: Drsingh.saurabh@gmail.com Orcid ID: 0000-0001-7513-4220Assistant Professor, Department of Gastroenterology, MMIMSR, Mullana, Ambala, Haryana, India. Email: paraag2789@gmail.com Orcid ID: 0000-0002-9192-3577Intern, Department of Gastroenterology, Himalyan Institute of Medical Sciences, Jolly Grant, Dehradun, Uttarakhand, India. Email: gurpreetchawla311@gmail.com Orcid ID: 0000-0003-0489-3523Professor and Head, Department of Radiation Oncology, Himalyan Institute of Medical Sciences, Jolly Grant, Dehradun, Uttarakhand, India. Email: meenugupta@srhu.edu.in Orcid ID: 0000-0002-7131-4408Professor, Department of Pathology, Himalyan Institute of Medical Sciences, Jolly Grant, Dehradun, Uttarakhand, India. Email: anuradhakusum@srhu.edu.in Orcid ID: 0000-0003-4439-6038