Tungphaisal, SChandeying, VSutthijumroon, SAeuwpadung, S2009-05-272009-05-271989-03-01Tungphaisal S, Chandeying V, Sutthijumroon S, Aeuwpadung S. Sublingual buprenorphine and pethidine for immediate postoperative pain relief in major gynecologic surgery: a comparative study. Journal of the Medical Association of Thailand. 1989 Mar; 72(3): 150-3http://imsear.searo.who.int/handle/123456789/44369Chotmaihet Thangphaet.The analgesic effect of sublingual buprenorphine 0.4 mg has been compared with pethidine 1 mg/kg given intramuscularly in 80 patients following major gynecologic operation. The results indicate a slower onset of action for sublingual buprenorphine in the first two hours (p less than 0.001), but it has a much longer duration and is more effective for pain relief (p less than 0.001) than pethidine. The main side-effects were nausea and vomiting which occurred after both treatments but with no significant difference.engAdministration, SublingualAdultBuprenorphine --administration & dosageFemaleGenital Diseases, Female --surgeryHumansInjections, IntramuscularMeperidine --administration & dosageMiddle AgedPain, Postoperative --drug therapyComparative Study