Chander, VikasRPS, SibiaMakkar, Gurjeen KaurSingh, ManjinderGarg, ParteekDua, Jasmeen Kaur2024-09-242024-09-242023-04Chander Vikas, RPS Sibia, Makkar Gurjeen Kaur, Singh Manjinder, Garg Parteek, Dua Jasmeen Kaur . Calcium and Phosphorus Metabolism in Patients with Congestive Heart Failure: A Cross-Sectional Study. International Journal of Medical Research Professionals. 2023 Mar; 9(2): 25-292454-63562454-6364https://imsear.searo.who.int/handle/123456789/231035Background: To study the role of calcium and phosphorus metabolism including the hormones (Vitamin D and PTH) controlling them in patients with congestive heart failure. While extensive studies are available regarding bone mineral metabolism in CKD patient with regard to CVD / HF similar studies in non-CKD patients are sparce, hence the present study. Methods: A cross sectional study was done on a total of 50 patients with signs, symptoms and Echocardiographic findings suggestive of heart failure admitted in medicine wards of Government Medical College Patiala. Patients with type 2 diabetes mellitus, chronic renal disease, thyroid disease and pregnant/lactating mothers were excluded from the study. Serum calcium, phosphorus, Vitamin D and parathyroid hormone were estimated in all patients. Results: The study population consisted of 54% males, 46% females. Mean age was 61.78 +/- 9.18 years. Majority of the patients had cardiac ejection fraction in the range of 22-28%. CAD and HT were present in 58% and 66% patients respectively. Mean values for Vitamin D levels were 19.5 ng/ml. While in patients with normal ejection fraction Vitamin D levels was 29.34ng/ml, it progressively decreased with decreasing ejection fraction, patients with ejection fraction of <20% had Vitamin D levels of 8.98 ng/ml. Similarly mean value of PTH was 89.07 pg/ml and progressively increased with decreasing ejection fraction. Maximum valve of 138.27 pg/ml was found in patients with ejection fraction of <20%. Serum phosphorus value progressively increased with decreasing ejection fraction. Similar trends were found for serum calcium levels also. Conclusion: There is an association between congestive heart failure and calcium and phosphorus metabolism (along with their controlling hormones Vitamin D and parathyroid hormones). Rising levels of phosphorus and PTH and decreasing levels of Vitamin D are directly related with progressive heart failure.CalciumPhosphorusMetabolismCongestive Heart FailureJournal ArticleIndiaDepartment of Internal Medicine, GMC And Rajindra Hospital, Patiala, Punjab, IndiaDepartment of Internal Medicine, GMC And Rajindra Hospital, Patiala, Punjab, IndiaDepartment of Internal Medicine, GMC And Rajindra Hospital, Patiala, Punjab, IndiaDepartment of Internal Medicine, GMC And Rajindra Hospital, Patiala, Punjab, IndiaDepartment of Internal Medicine, GMC And Rajindra Hospital, Patiala, Punjab, IndiaDepartment of Internal Medicine, GMC And Rajindra Hospital, Patiala, Punjab, India