Jain, PrekshaJain, ShreyaBhardava, Vishal Kumar2024-12-072024-12-072024-01Jain Preksha, Jain Shreya, Bhardava Vishal Kumar. Significance of MRI in the Evaluation of Epilepsy Patients. Indian Journal of Applied Basic Medical Sciences. 2024 Jan; 26A(1): 1-100975-89172249-7935https://imsear.searo.who.int/handle/123456789/242238Background/Aims: Recurrent seizures that are not brought on by a sudden systemic or neurological injury are the hallmark of epilepsy, a chronic illness.1 The clinical manifestation of aberrant, excessive neuronal activity originating in the cerebral cortex's grey matter is an epileptic seizure.2 A paroxysmal change in neurologic function brought on by abnormally high neuronal electrical activity is known as a seizure.1 The superior soft tissue contrast of MR imaging, which permits a detailed representation of anatomy and eliminates the beam-hardening artefact in the basal brain that is present with CT, has made it the most valuable and diagnostically valuable tool for preoperative localization of epileptogenic focus. Additionally, MR imaging allows for multiplanar imaging.1 Material and methods: A prospective study was carried out at the Radiodiagnosis Department at Dhiraj Hospital, SBKS MI&RC, Vadodara, Gujarat. All individuals who had clinical symptoms and indicators of epilepsy and were sent to the Department of Radio-Diagnosis. The MRI scanner used for the study was the Siemens. Using the 1.5T SIEMENS MAGNETOM-ESSENZA system, MRI scans were performed on each subject. The study aimed to include a minimum of 100 cases; however, there is potential to include more cases based on availability throughout the study time. 220 cases in all were examined. Results: In our study 220 patients who were clinically diagnosed of epilepsy were undergone MRI examination of the brain. The MRI findings were normal in 100(45.4%) cases and revealed spectrum of abnormalities in 120(54.5%) cases. The common abnormalities were cerebral infarction with gliosis (22.2%), infections –NCC (8.6%) and tuberculoma (2.7%), cerebral atrophy (7.2%), venous thrombosis (3.6%), developmental malformations (3.1%), cavernomatous malformations (1.8%), glioma (1.82%), meningioma (1.3%), tuberous sclerosis (0.9%), viral encephalitis findings (0.4 %) and AV malformation (0.4%)were among the abnormal findings. Conclusion: We conclude that MRI plays a significant role in patients presenting with epilepsy with MRI epilepsy protocol to confirm or rule out any organic or developmental lesions. In our study, it was observed that most common neuroimaging abnormalities associated were cerebrovascular diseases & infections. Most common age group in our study was 16-30 years with male predominance.MRI. EVALUATIONEPILEPSYJournal ArticleIndiaResident, Department of Radiodiagnosis, SBKS MI&RC, Vadodara, IndiaResident, Department of Radiodiagnosis, SBKS MI&RC, Vadodara, IndiaProfessor, Department of Radiodiagnosis, SBKS MI&RC, SUMANDEEP VIDHYAPITH, PIPARIYA Vadodara, India