Kapoor, SeemaRatan, Simmi KKashyap, RaviMittal, S KRajeshwari, KRawat, HVerma, Jyoti2002-09-082009-05-302002-09-082009-05-302002-09-08Kapoor S, Ratan SK, Kashyap R, Mittal SK, Rajeshwari K, Rawat H, Verma J. Detecting protein losing enteropathy by Tc-99m dextran scintigraphy: a novel experience. Indian Journal of Pediatrics. 2002 Sep; 69(9): 761-4http://imsear.searo.who.int/handle/123456789/84280OBJECTIVE: To evaluate protien using enteropathy by Tc-99m dextran scintigraphy. METHODS: Methods for detecting protein loss from the intestine revolve around fecal nitrogen excretion, the clearance of alpha-1 antitrypsin in stools and by endoscopic biopsy. RESULT: The diagnosis of protein-losing enteropathy (PLE) can also be established by a scintigraphic method that is noninvasive, simple and requires no patient preparation or motivation. This diagnostic modality can also delineate the site of protein loss, thereby offering a targeted approach, and if need be, surgery. Radiolabelling of a non-protein, noncolloidal, nonparticulate and biofriendly molecule like dextran with Technetium-99m for imaging enteric protein loss was utilized in imaging eight children with PLE. CONCLUSION: The results were encouraging. The authors advocate the use of this diagnostic tool in identifying patients with PLE, particularly in the pediatric age group.engChildChild, PreschoolCohort StudiesDextrans --diagnostic useFemaleHumansIndiaMaleOrganotechnetium Compounds --diagnostic useProspective StudiesProtein-Losing Enteropathies --diagnosisSensitivity and SpecificitySeverity of Illness IndexJournal Article