Deepa, TThirrunavukkarasu, N2013-03-112013-03-112010-07Deepa T, Thirrunavukkarasu N. Saliva as a potential diagnostic tool. Indian Journal of Medical Sciences. 2010 July; 64(7) 293-306.http://imsear.searo.who.int/handle/123456789/145543Saliva is a complex fluid consisting of secretions from the major and minor salivary glands. Gland-specific saliva can be used to diagnose any pathology from the specific major salivary gland. Whole saliva has serum constituents that are derived from the local vasculature of the salivary glands and gingival crevicular fluid. Saliva, as a diagnostic fluid, has distinctive advantages over serum as whole saliva can be collected non-invasively by individuals with limited training using simple equipments. This review aimed to explore the diagnostic applications of saliva in systemic and oral diseases. Analysis of saliva can offer a cost-effective approach to screen for a larger population. Salivary analysis may be useful for diagnosing systemic oral disorders, as well as for monitoring hormone and therapeutic levels of drug.enBiomarkersSalivadiagnostic toolsystemic diseaseAutoimmune Diseases --diagnosisBiological MarkersCardiovascular Diseases --diagnosisGenetic Diseases, Inborn --diagnosisHumansKidney Diseases --diagnosisMouth Diseases --diagnosisNeoplasms --diagnosisPeriodontics --diagnosisSaliva --analysisDental Caries --diagnosisArticle