Padmasree, Gaddam2020-01-022020-01-022019-03Padmasree Gaddam. Clinical Evaluation of Soft Tissue Sarcoma: An Observational Study on 26 Cases in a Tertiary Care Teaching Hospital. IJSS Journal of Surgery. 2019 Mar; 5(2): 11-162321-63792395-1893http://imsear.searo.who.int/handle/123456789/189887Introduction: “Sarkoma” (Greek) means fleshy growth. Tumors that arise from common embryonic ancestry, the primitive mesoderm, are known as sarcomas. The aim of this observational study is to evaluate the demographic distribution, histopathological presentation, clinical presentation, and various modes of management of soft tissue sarcomas (STS). Materials and Methods: The present study is a descriptive hospital-based study conducted in the Department of General Surgery in a tertiary care hospital from November 2013 to November 2015. Patients of all ages and both genders presenting to the outpatient department of general surgery with malignant soft tissue tumors were included in the study. After clinically diagnosing as a case of STS, each patient was subjected to various necessary clinical and biochemical investigations pertaining to confirmation of the diagnosis and the patient was treated according to the standard management protocol following in this institution. Observations and Results: Clinical parameters of evaluation such as incidence of STS, gender distribution, time of presentation of tumors, anatomical and histopathological distribution, presence of lymphadenopathy, occurrence of distant metastasis, mode of treatment, recurrence rate, and follow-up were evaluated in each patient and conclusions were drawn. Data were expressed in absolute numbers and percentages and tabulated statistically. Conclusion: STS is a rare malignancy with poor prognosis. With the advent of immunohistochemistry and combined therapies, survival rate and quality of life can be improved significantly.Journal ArticleIndiaProfessor and HOD, Department of General Surgery, ACSR Government Medical College, SPSR Nellore, Andhra Pradesh, India