Patel, Harsha UPatel, Ravi SPatel, Chhaganbhai N2014-06-022014-06-022013-03Patel Harsha U, Patel Ravi S, Patel Chhaganbhai N. Synthesis and antihypertensive activity of some quinazoline derivatives. Journal of Applied Pharmaceutical Science. 2013 Mar; 3(3): 171-174.http://imsear.searo.who.int/handle/123456789/151588Quinazoline derivatives have been very well known for Antihypertensive activity. Seven new Quinazoline derivatives are synthesized by three steps. Purity of compound is checked by TLC monitoring. All synthesized compounds are confirmed by UV, IR, Mass and H1NMR. All synthesized compound were screened for α1-adrenergic receptor blocking activity. Amongst all synthesized compounds 4a & 4e showed better activity.enQuinazolin-4-(3H)-oneα1-adrenergic receptors blocking activityMass spectraNuclear Magnetic Resonance spectraArticle