Kapoor, SeemaMukherjee, Sharmila BanerjeeShroff, DaraiusArora, Ritu2015-12-242015-12-242011-09Kapoor Seema, Mukherjee Sharmila Banerjee, Shroff Daraius, Arora Ritu. Dysmyelination of the Cerebral White matter with Microdeletion at 6p25. Indian Pediatrics. 2011 Sptember; 48(9): 727-729.http://imsear.searo.who.int/handle/123456789/168960A 6-year old boy presented with mental retardation, hypotonia, abnormal facies, impaired hearing, protuberant eyes, visual impairment, short stature, Axenfeld- Rieger anomaly, a bicuspid aortic valve, and bilateral sensorineural deafness. CT scan of head suggested dysmyelination of the subcortical and periventricular white matter. FISH revealed a subtelomeric microdeletion encompassing both FOXC1 and FOXF2 loci within 6p25. Dysmyelination of the central nervous system has been infrequently described earlier in patients with 6p25 deletion.en6p25 microdeletionAxenfeld-Rieger anomalyDysmyelinationArticle