Lin, K THuang, S HKao, C LHuang, K MYu, J CHung, T PChou, M YLiu, W TFang, C TKuo, Y T2009-05-272009-05-271987-06-01Lin KT, Huang SH, Kao CL, Huang KM, Yu JC, Hung TP, Chou MY, Liu WT, Fang CT, Kuo YT. An autopsy-proved case of AIDS in Taiwan. Asian Pacific Journal of Allergy and Immunology. 1987 Jun; 5(1): 25-31http://imsear.searo.who.int/handle/123456789/37046Published by the Allergy and Immunology Society of Thailand.The first case of AIDS positively identified in a non-foreigner in Taiwan was a 25-year-old unmarried male who had practiced homosexuality for ten years. The patient began to have abdominal pain accompanied with loose stools and weight loss in June 1985, followed by fever, cough, headache, dizziness, and loss of memory. Facial hyperpigmentation and extensive oroesophageal candidiasis were noted. Laboratory studies showed severe lymphopenia with a reversed T-helper to T-suppressor ratio, cutaneous anergy and polyclonal gammopathy. Human immunodeficiency virus (HIV) antibodies were positive by ELISA and Western blot, and the virus was isolated from the blood. At autopsy, disseminated cytomegalovirus infection, extensive CNS toxoplasmosis and early lesions of Kaposi's sarcoma were demonstrated. The detection of HIV in the adrenal medulla supports the consensus that the virus is neurotropic.engAcquired Immunodeficiency Syndrome --diagnosisAdultAutopsyBrain --pathologyElectrophoresis, Polyacrylamide GelEnzyme-Linked Immunosorbent AssayHIV --isolation & purificationHomosexualityHumansImmunologic TechniquesMaleTaiwanCase Reports