Sakina, M RKhan, E AHamdard, M EDandiya, P C1989-01-012009-06-011989-01-012009-06-011989-01-01Sakina MR, Khan EA, Hamdard ME, Dandiya PC. A neuropsychopharmacological profile of "Cinkara", a polyherbal preparation. Indian Journal of Physiology and Pharmacology. 1989 Jan-Mar; 33(1): 43-6http://imsear.searo.who.int/handle/123456789/107003"Cinkara", a polyherbal preparation reduced pentobarbitone induced hypnosis in mice, decreased apomorphine induced fighting, aggression and stereotypy and increased amphetamine induced aggregated toxicity in mice. It also increased immobility of rats in forced swimming test, an action which was not blocked by chlor-promazine, and increased ambulation in open arena test. It did not modify electrically induced convulsions or haloperidol catalepsy. It is suggested that the preparation possesses a central nervous system stimulant activity but unlike other CNS stimulants, it lowers aggressive activity in rats.engAggression --drug effectsAnimalsApomorphine --pharmacologyBehavior, Animal --drug effectsBrain Chemistry --drug effectsCatatonia --chemically inducedElectroshockFemaleHaloperidol --pharmacologyMaleMicePentobarbital --pharmacologyPlants, MedicinalRatsSleep --drug effectsStereotyped Behavior --drug effectsJournal Article