Sandhu, JKRai, SSandhu, KK.2025-05-092025-05-092024-10Sandhu JK, Rai S, Sandhu KK.. Systemic lupus erythematosus presenting as toxic epidermal necrolysis: a case report . International Journal of Contemporary Pediatrics. 2024 Oct; 11(10): 1474-14772349-32832349-3291https://imsear.searo.who.int/handle/123456789/246326Systemic lupus erythematosus is an autoimmune inflammatory disease with complex etiology. Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) represent a spectrum of skin lesions characterized by rashes, exfoliation, and sloughing usually following drug intake. Occasionally, TEN-like cutaneous manifestations have also been described with systemic lupus erythematosus. Recognition of lupus in a child presenting with TEN-like skin changes is clinically challenging and requires a high degree of suspicion. We present a case of a 9-year-old female with SJS/TEN like lesions following drug intake and on evaluation was found to have systemic lupus erythematosus.EpidermisLupus erythematosusCutaneousBlisterAutoimmuneJournal ArticleIndiaDepartment of Pediatrics, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, IndiaDepartment of Pediatrics, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, IndiaDD Eye Institute and Lasik Laser Center, Kota, Rajasthan, India