Arewar, ADhankikar, SBesekar, SBhosle, MBesekar, D2025-06-182025-06-182025-06Arewar A, Dhankikar S, Besekar S, Bhosle M, Besekar D. Clinical insights and management strategies in Takotsubo cardiomyopathy: a comprehensive review. International Journal of Basic & Clinical Pharmacology. 2025 Jun; 14(3): 423-4272319-20032279-0780https://imsear.searo.who.int/handle/123456789/248648Takotsubo cardiomyopathy (TCM) is characterized by transient left ventricular dysfunction typically triggered by stressors, presents diagnostic challenges resembling acute coronary syndrome (ACS). This comprehensive review synthesizes diverse triggers (stress, illness, therapies), diagnostic complexities (variability in criteria, imaging modalities), and management strategies (supportive care, tailored medications). Despite favourable outcomes with reversible ventricular dysfunction, heightened risks in specific cohorts (e.g., malignancies, post-PCI) underscore the need for refined diagnostic criteria and optimized therapies. Prospective studies are essential to enhance understanding and management of TCM, aiming to improve clinical outcomes and patient care.Takotsubo cardiomyopathyBroken heart syndromeStress cardiomyopathyManagement strategiesJournal ArticleIndiaEast State Tennessee University, TN, USAEast State Tennessee University, TN, USADepartment of Pharmacology, JNMC, Sawangi, Wardha, Maharashtra, IndiaDivision of Criminology and Forensic Science, Karunya Institute of Technology and Sciences, Coimbatore, Tamil Nadu, IndiaMOIL Limited Nagpur, Maharashtra, India