R. RavindranIyer SaraswatiDeshpande Mangala2024-09-242024-09-242023-03R. Ravindran, Iyer Saraswati, Deshpande Mangala. The Role of Sympathetic Skin Response in Assessing Autonomic Function in Normal Adults. International Journal of Clinical and Biomedical Research. 2023 Jan; 9(1): 1-62395-04712521-0394https://imsear.searo.who.int/handle/123456789/226857Background:Sympathetic Skin Response (SSR) is a simple, non-invasive and reproducibletest to assess the impairment of the sympathetic fibers of the peripheral nerves. It measuresthe change in electrical skin potential to a variety of stimuli. The objective of this study was toassess SSR in a sample of normal healthy adults.Method:25 normal healthy adults whovolunteered to participate were assessed for SSR in their foot and hand. SSR was assessedusing Neurowerk EMG/NCV equipment capable of assessing SSR. Electrical current was usedon the median nerve at the wrist to elicit SSR.Results:SSR was elicited in all 25participants. The mean SSR latency and SSR Amplitude for the hand were 1.2 (+/- 0.42) secsand 2503 (+/- 1424) micro Volt respectively. The mean SSR Latency and SSR Amplitude forthe foot were 1.8 (+/- 0.44) secs and 1749 (+/- 1252) micro Volts respectively. It was observedthat there was no significant difference in the SSR values when compared between male andfemale participants, so gender had no effect on SSR values. There was no association of SSRvalues with the BMI of the participants. Characteristics of the SSR curves were discussed.Conclusion:Mean values of SSR latency measured at hand and foot are 1.2 (+/- 0.42) secsand 1.8 (+/- 0.44) secs respectively. Mean values of SSR amplitude measured at hand and footare 2503 (+/- 1424) micro Volts and 1749 (+/- 1252) micro Volts respectively. Gender had noeffect on SSR values in this study.Sympathetic Skin ResponseAutonomic FunctionHealthy AdultsElectrical CurrentJournal ArticleIndiaLecturer, Department of Physiotherapy, All India Instituteof Physical Medicine and Rehabilitation, MumbaiProfessor & Head, Physiotherapy School & Centre, GSMC & KEM Hospital, Parel, MumbaiFormer Director, VSPM's College of Physiotherapy, Nagpur