Naresh, K NSivasankaran, PVeliath, A J1993-06-012009-05-311993-06-012009-05-311993-06-01Naresh KN, Sivasankaran P, Veliath AJ. Platelet function in acute leukemias. Journal of the Association of Physicians of India. 1993 Jun; 41(6): 377-8http://imsear.searo.who.int/handle/123456789/95322Bleeding time, clot retraction, platelet factor 3 availability and platelet aggregation in response to ADP, epinephrine, collagen and ristocetin were studied in 13 cases of acute leukemia which included 5 cases of acute myeloid leukemia, 2 of chronic myeloid leukemia in blast crisis and 6 of acute lymphoblastic leukemia. More than one abnormality was seen in all the patients. Defects in bleeding time, clot retraction and platelet factor 3 availability were encountered in 43% of cases. Platelet aggregation responses to all the reagents were significantly impaired. There was, however, no consistency in the pattern of the defects.engBlast Crisis --bloodBlood Platelets --physiologyHumansLeukemia, Myelogenous, Chronic, BCR-ABL Positive --bloodLeukemia, Myeloid, Acute --bloodPlatelet Aggregation --physiologyPlatelet Function TestsPrecursor Cell Lymphoblastic Leukemia-Lymphoma --bloodJournal Article