Jena, SSwain, J PMishra, S2005-04-282009-05-282005-04-282009-05-282005-04-28Jena S, Swain JP, Mishra S. Fnac study of histoid nodule: an early tool for diagnosis. Indian Journal of Leprosy. 2005 Apr-Jun; 77(2): 135-9http://imsear.searo.who.int/handle/123456789/55100Histoid lesion, a variety of lepromatous leprosy, is due to alteration in the growth pattern of Mycobacterium leprae, possibly due to loss of immunity in localized areas. The distinction is based on cellular morphology by demonstrating pallisading arrangement of multi-layered spindle-shaped histocytes. Cytodiagnosis by fine needle aspiration cytology is therefore an early tool to recognize the histoid variety, differentiating it from a conventional LL module, as it is a simple and less traumatic procedure.engAdultBiopsy, Fine-Needle --methodsCytodiagnosisHistocytochemistryHumansLeprosy, Lepromatous --microbiologyMaleMycobacterium leprae --cytologyCase Reports