Verma, NGaur, NAwasthi, SBajaj, VSharma, SMahajan, S2025-06-192025-06-192025-03Verma N, Gaur N, Awasthi S, Bajaj V, Sharma S, Mahajan S. Crystallizing galactocele: A rare case report and review of literature. Indian Journal of Pathology & Microbiology. 2025 Mar; 68(1): 198-2000377-49290974-5130https://imsear.searo.who.int/handle/123456789/249952Crystallizing galactocele is an uncommon condition that produces a viscous, chalky substance on fine needle aspiration cytology. (FNAC). Both the diagnosis and the management of this illness include the use of FNAC. Here, we discuss the case of a 25-year-old nursing woman who experienced left breast edema lump for two years. The upper outer quadrant of the leftt breast was involved by the hard, small, non-tender, and movable enlargement. The lesion's FNAC produced a thick, milky, and chalky substance. Numerous semi-transparent crystals of various sizes and shapes with angulated edges could be seen in cytological smears against a background of granular and amorphous proteinaceous material. A diagnosis of crystallizing galactocele was made on the basis of the patient's clinical history of lactation and characteristic cytological findings. Due to the rarity of this condition—to the best of our knowledge, less than ten cases of crystallizing galactocele have been documented in medical literature.Crystallizing galactocelecytologyFNACJournal ArticleIndiaDepartment of Pathology, Panagarh Military Hospital, Chandipur, West BengalDepartment of Pathology, Military Hospital, Jalandhar, PunjabINHS DhanvantariDepartment of Pathology, Armed Forces Medical College, Pune, Maharashtra, IndiaDepartment of Pathology, Armed Forces Medical College, Pune, Maharashtra, IndiaDepartment of Pathology, Panagarh Military Station, Chandipur, West Bengal, India