Singh, DeekshaAgarwal, ShilpiChander, RamAgarwal, KiranSingh, Preksha2019-11-252019-11-252018-08Singh Deeksha, Agarwal Shilpi, Chander Ram, Agarwal Kiran, Singh Preksha. Direct Immunofluorescence Profile Of Lichen Planus - A Fresh Look On Old Disease. A Study Of 15 Cases. Global Journal For Research Analysis. 2018 Aug; 7(8): 26-282277-8160http://imsear.searo.who.int/handle/123456789/184787Introduction: Lichen planus (LP) is a chronic inflammatory mucocutaneous diasease that is often diagnosed on the basis of clinical &/or histopathologic findings. However, it has some characteristic direct immunofluorescence (DIF) findings that can help in diagnosing confusing cases.Aim:We analyzed DIF findings in skin biopsy in LP compared to histopathology. Materials & methods: A skin biopsy of lesion was taken from 15 cases of LP(13 classic LP & 2 LP pigmentosus) & subjected to histopathology & DIF examination. Results:The sensitivity of histopathology and DIF was found to be 100% & 93.3% respectivelyfor the diagnosis of LP & LPP.Direct immunofluorescenceLichen planusskin biopsyJournal ArticleIndiaMD, Senior Resident Pathology, Lady Hardinge Medical College, New DelhiMD, Director Professor Pathology, Lady Hardinge Medical College, New DelhiMD, Director Professor & Head, Department of Dermatology and STD, Lady Hardinge Medical College, New DelhiMD, Junior Resident, Department of Dermatology and STD, Lady Hardinge Medical College, New Delhi