Sharma, AGupta, RRam, JGupta, A1997-09-252009-05-291997-09-252009-05-291997-09-25Sharma A, Gupta R, Ram J, Gupta A. Topical ketorolac 0.5% solution for the treatment of vernal keratoconjunctivitis. Indian Journal of Ophthalmology. 1997 Sep; 45(3): 177-80http://imsear.searo.who.int/handle/123456789/70483The efficacy of topical ketorolac 0.5% in treatment of vernal keratoconjunctivitis (VKC) was evaluated in a randomised double-blind prospective trial in 21 patients. Ketorolac treated eyes showed 50.7% reduction in main symptoms of itching compared to 33.3% relief in placebo treated eyes after 2 weeks of treatment (p < 0.01). Photophobia, ropy discharge, and conjunctival injection also lessened by 39.9%, 31.6%, and 39.1%, respectively, in ketorolac treated eyes compared to 23.8%, 17.3%, and 20.3% in placebo group. Transient stinging sensation was observed in 3 (14.3%) patients on ketorolac therapy. This study shows efficacy of ketorolac 0.5% solution in controlling symptoms in VKC.engAdministration, TopicalAdolescentAdultAnti-Inflammatory Agents, Non-Steroidal --administration & dosageChildChild, PreschoolConjunctivitis, Allergic --drug therapyDouble-Blind MethodFemaleHumansKetorolacMaleOphthalmic SolutionsProspective StudiesSafetyTolmetin --administration & dosageTreatment OutcomeClinical Trial