Jayasri, PKaliaperumal, SubashiniBehera, GeetaStephen, Mary2023-08-252023-08-252022-12Jayasri P, Kaliaperumal Subashini, Behera Geeta, Stephen Mary. Safety and efficacy of Aurolab aqueous drainage implant in refractory glaucoma: A prospective study. Indian Journal of Ophthalmology. 2022 Dec; 70(12): 4212-42161998-36890301-4738http://imsear.searo.who.int/handle/123456789/224726Purpose: This study was conducted to assess the intraocular pressure (IOP) control and postoperative complications following a non?valved glaucoma drainage device (GDD) surgery in refractory glaucoma. Methods: This was a prospective interventional study conducted on patients with glaucoma refractory to maximal medications or failed surgical treatment who underwent Aurolab aqueous drainage implant (AADI; Aurolabs, India) surgery. Primary outcome measures were IOP control, postoperative complications, and reduction in the number of antiglaucoma medications (AGM). Results: Thirty-four eyes were analyzed and the mean follow?up was 16.06 ± 5.63 months. The preoperative median (Q1, Q3) IOP was 31 mmHg (28, 36.5) which decreased to 12 mmHg (12, 14) at 6 months postoperatively. The median (Q1, Q3) number of AGMs decreased from 3 (3, 4) to 0 (0, 1). Significant complications like implant extrusion and tube exposure were noted in two eyes. The total success and failure rates at 6 months were 91.1% and 8.8%, respectively. Conclusion: AADI is effective in achieving target IOP and significantly reduces the use of AGMs with good safety in the short term. Long?term follow?up studies are needed to assess long?term IOP control and cost?effectiveness.Aurolab aqueous drainage implant (AADI)glaucoma drainage deviceglaucoma surgeryintraocular pressure (IOP)refractory glaucomaJournal ArticleIndiaDepartment of Ophthalmology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India