Goonetilleke, A KMunasingha, J MGuruge, D SSamaraweera, D SWeerasena, O V2009-05-282009-05-281998-03-13Goonetilleke AK, Munasingha JM, Guruge DS, Samaraweera DS, Weerasena OV. Plasma pharmacokinetics of a generic amoxycillin and the innovator brand: a comparison. The Ceylon Medical Journal. 1998 Mar; 43(1): 16-8http://imsear.searo.who.int/handle/123456789/48191The Ceylon Medical Journal.OBJECTIVE: To compare the bioavailability and plasma pharmacokinetics of a generic brand of amoxycillin (State Pharmaceutical Manufacturing Coporation) selected from the lower price range, with that of the innovation brand (Amoxil, Beecham). DESIGN: Sixteen healthy adult volunteers were allotted to two groups and each group was given a test dose of amoxycillin from each brand. Blood samples were collected at 0, 2, 3 and 4 hours thereafter plasma levels were assayed using high performance liquid chromatography. RESULTS: Analysis of results show that the generic product had similar bioavailability and pharmacokinetics when compared with the innovator product. CONCLUSION: The quality assured generic amoxycillin tested had similar bioavailability as a more costly branded version.engAdministration, OralAdolescentAdultAmoxicillin --administration & dosageArea Under CurveBiological AvailabilityChromatography, High Pressure LiquidDrugs, Generic --administration & dosageFemaleHumansMalePenicillins --administration & dosageReference ValuesComparative Study