Mokashi, A JShirahatti, R GPrabhu, S KVagholkar, K R1992-07-012009-06-021992-07-012009-06-021992-07-01Mokashi AJ, Shirahatti RG, Prabhu SK, Vagholkar KR. Pathological rupture of malarial spleen. Journal of Postgraduate Medicine. 1992 Jul-Sep; 38(3): 141-2http://imsear.searo.who.int/handle/123456789/117400Two cases of spontaneous rupture of malarial spleen are reported here. One of them was a male who was on chloroquine for an acute attack of malaria. While on therapy, he complained of pain in left hypochondrium followed by palpitations. The other patient was a female who was admitted for continuous dull aching pain and fever. In both the patients, exploratory laparotomy revealed an enlarged spleen with tear. Splenectomy was performed. Histopathological examination revealed dilated congested sinusoid with follicular atrophy, and RBCs with malarial parasites. The post-operative course was smooth in both patients.engAdultFemaleHumansMalaria, Vivax --pathologyMaleMiddle AgedRupture, SpontaneousSplenectomySplenic Rupture --pathologyPathological rupture of malarial spleen.Case Reports