Chumworathayi, BanditKleebkaow, Pilaiwan2009-05-272009-05-272007-10-12Chumworathayi B, Kleebkaow P. Primary non-gestational uterine cervical choriocarcinoma with metaplastic transformation from squamous cells. Asian Pacific Journal of Cancer Prevention. 2007 Oct-Dec; 8(4): 642-4http://imsear.searo.who.int/handle/123456789/37905Asian Pacific Journal of Cancer Prevention.BACKGROUND: Primary non-gestational uterine cervical choriocarcinoma is very unusual and although it has been hypothesized that it can arise by metaplastic transformation of cervical epithelium, solid evidence has been lacking. CASE: Primary non-gestational uterine cervical choriocarcinoma was diagnosed in a 47-year-old, woman undergoing tubal resection 17 years previously. A histologically- and immunohistochemically-confirmed, non-gestational cervical choriocarcinoma could be diagnosed in which there was metaplastic transformation from squamous cells . The patient underwent 5 courses of an actinomycin-D chemotherapeutic regimen and radical hysterectomy with bilateral pelvic lymphadenectomy. CONCLUSION: Primary non-gestational uterine cervical choriocarcinoma may indeed arise from metaplastic transformation of epithelial tissue.engAntibiotics, Antineoplastic --therapeutic useCarcinoma, Squamous Cell --pathologyCell Transformation, NeoplasticChoriocarcinoma, Non-gestational --drug therapyDactinomycin --therapeutic useFemaleHumansHysterectomyLymph Node ExcisionMetaplasia --drug therapyMiddle AgedPelvic Neoplasms --surgeryUterine Cervical Neoplasms --drug therapyCase Reports