Hari Krishnan, KLeema Pauline, CKumaresan, GVasantha Mallika, T K2005-01-082009-05-272005-01-082009-05-272005-01-08Hari Krishnan K, Leema Pauline C, Kumaresan G, Vasantha Mallika TK. Megalencephalic leukoencephalopathy with subcortical cysts. Indian Pediatrics. 2005 Jan; 42(1): 60-3http://imsear.searo.who.int/handle/123456789/12675Megalencephalic leukoencephalopathy with subcortical cysts is a rare disease first described in 1995. It is characterized by macrocephaly and early onset white matter degeneration. We report two siblings who were diagnosed to have this disease. This disease must be included in differential diagnosis of macrocephaly with early onset leukoencephalopathy.engBrain Neoplasms --diagnosisCentral Nervous System Cysts --diagnosisChild, PreschoolHereditary Central Nervous System Demyelinating Diseases --diagnosisHumansMaleMutationPolymorphism, GeneticCase Reports