Malik, Altaf HussainVaishnov, KalpeshMajeed, ShabnumSheikh, TafazulShah, Altaf H.2025-08-132025-08-132025-02Malik Altaf Hussain, Vaishnov Kalpesh, Majeed Shabnum, Sheikh Tafazul, Shah Altaf H. . Bisphosphonate induced necrosis of jaws-the emerging challenging epidemic. Annals of International Medical and Dental Research. 2025 Feb; 11(1): 40-432395-28222395-2814https://imsear.searo.who.int/handle/123456789/250011Background: The bisphosphonates are widely prescribed drugs to prevent bone resorption, however, are associated with the potential risk of osteonecrosis of jaws in patients receiving dental treatment. Methods: The study was designed to evaluate the chances of osteonecrosis in patients referred for management in whom dental treatment was carried out of negligence or lack of knowledge. Results: Out of 74 patients studied, 16 patients had developed osteonecrosis, particularly after dental extraction, and out of 16 patients, 12 patients were having underlying malignancy. Conclusion: Medication-induced necrosis of jaws is more in patients with underlying malignancy or other comorbidities compared to patients who are not suffering from malignancy, and dental treatment particularly extraction is a trigger in such patients for developing the debilitating condition.BisphosphonatesMRONJosteonecrosis.Journal ArticleIndiaAssistant Professor, Department of OMFS, GDC Srinagar, JK, IndiaDepartment of Prosthodontics, Karnavati University, Ahmedabad, Gujarat, IndiaDepartment of Anesthesia, Government Medical College, Srinagar, Jammu and Kashmir, IndiaDepartment of Dentistry, SKIMS Medical College, Srinagar, Jammu and Kashmir, IndiaDepartment of Community Dental Sciences, School of Dentistry, Marquette University, Milwaukee, Wisconsin, United States