Bisht, PKhetrapal, SSehgal, SJetley, SJain, V.2023-07-142023-07-142023-03Bisht P, Khetrapal S, Sehgal S, Jetley S, Jain V.. An Unusual Case of DRESS Syndrome Presenting with Marked Leucocytosis.. Light House Polyclinic. 2023 Mar; 22(1): 1-20972-5997http://imsear.searo.who.int/handle/123456789/218346Drug reaction with eosinophilia and systemic symptom (DRESS) syndrome is a rare severe drug-induced idiosyncratic hypersensitivity characterized by maculopapular and/or erythrodermic eruption, fever, peripheral lymphadenopathy, eosinophilia or atypical lymphocytosis, and visceral organ involvement. The estimated incidence of this syndrome ranges from 1/1000 to 1/10,000 drug exposures. In this report, we describe a case of DRESS syndrome in a young female with a unique presentation. The DRESS syndrome can be difficult to diagnose as its clinical findings can mimic those of other systemic diseases. This case emphasizes the importance of incorporation of the patient’s clinical and medication history in the interpretation of hematological investigations.DRESS SyndromeLeucocytosiseosinophiliaAtypical lymphocytosisSulfasalazineJournal ArticleIndiaDepartment of PathologyDepartment of PathologyDepartment of PathologyDepartment of PathologyDepartment of Medicine, Hamdard Institute of Medical Sciences and Research, New Delhi, India.