Infant Pulmonary Function Tests in Children with Airway Anomalies and Correlation with Bronchoscopy Findings
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Date
2024-05
Journal Title
Journal ISSN
Volume Title
Publisher
The Indian Academy of Pediatrics
Abstract
Objectives: To evaluate the role infant pulmonary function tests (Tidal Breathing Flow Volume Loops, TBFVL) in children with airway anomalies and to correlate the TBFVL so obtained with bronchoscopy findings. Methods: In this prospective cohort study, we enrolled children aged 0-2 years with airway anomalies and performed TBFVL and bronchoscopy. The primary outcome measure was graphic pattern of TBFVL in laryngomalacia. Secondary outcome measures were types of TBFVL results in various airway anomalies and controls. Results: Out of 53 children enrolled, 28 (52.3%) had laryngomalacia. Pattern 3 (fluttering of inspiratory limb) was commonest TBFVL pattern in laryngomalacia. Among TBFVL parameters, the ratio of inspiratory time to expiratory time (Ti/Te) and tPTEF/tE was significantly high in children with isolated laryngomalacia compared to controls. At six months of follow-up, TBFVL pattern 1 (normal) became the commonest pattern. Conclusion: A particular type of airway anomaly may have a characteristic graphic pattern in TBFVL and TBFVL pattern may indicate improvement in airway anomalies in follow-up.
Description
Keywords
Fluttering pattern, Laryngomalacia, Tracheomalacia, Tidal Breathing Flow Volume Loop
Citation
Pathania Amit, Jat Kana Ram, Sankar Jhuma, Lodha Rakesh, Kabra Sushil K . Infant Pulmonary Function Tests in Children with Airway Anomalies and Correlation with Bronchoscopy Findings. Indian Pediatrics. 2024 May; 61(5): 419-425