Clinico-etiological and EEG profile of neonatal seizures.

dc.contributor.authorKumar, Ajayen_US
dc.contributor.authorGupta, Ashishen_US
dc.contributor.authorTalukdar, Bibeken_US
dc.date.accessioned2007-01-01en_US
dc.date.accessioned2009-05-30T12:09:27Z
dc.date.available2007-01-01en_US
dc.date.available2009-05-30T12:09:27Z
dc.date.issued2007-01-01en_US
dc.description.abstractOBJECTIVE: To evaluate clinical, etiological and EEG profile of neonatal seizures. METHODS: In all the neonates enrolled in the study baseline information recorded was sex, gestational age, weight, ponderal index etc. Clinical profile of seizure episode included age at onset of seizure, type and duration of seizure, associated autonomic changes, medication given, response time to medication and possible cause. Relevant maternal history including antenatal and peripartum history was recorded. Relevant history and examination of newborn were noted. Essential investigations done in all subjects included blood glucose, serum calcium, serum sodium and arterial pH. USG cranium and EEG were done at earliest in all the subjects wherever feasible. Additional investigations were done as guided by history, physical examination and essential investigations. RESULTS: Ninety babies with clinical seizures were enrolled into the study over one year period with an overall incidence of 1.17% (0.69% in term babies and 6.14% in preterm babies). Abnormal EEG's were found in one third cases out of 60 EEG's done in 90 babies. 26.7% of babies with perinatal asphyxia had abnormal EEG's (8/30). While 60% of babies with HIE II had abnormal discharges, background activity was suppressed in 66.66% EEG's in babies with HIE III. CONCLUSIONS: Overall incidence of neonatal seizures was 11.7/1000 live births, majority being preterm very low birth weight babies before 5 days of life. Perinatal asphyxia was responsible in 44.44% babies followed by metabolic abnormalities (23.33%). EEG abnormalities were present in 33.34% babies.en_US
dc.description.affiliationDepartment of Pediatrics, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi, India. ajayanu@vsnl.neten_US
dc.identifier.citationKumar A, Gupta A, Talukdar B. Clinico-etiological and EEG profile of neonatal seizures. Indian Journal of Pediatrics. 2007 Jan; 74(1): 33-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/80401
dc.language.isoengen_US
dc.source.urihttps://medind.nic.in/icb/icbai.shtmlen_US
dc.subject.meshAnticonvulsants --therapeutic useen_US
dc.subject.meshCohort Studiesen_US
dc.subject.meshElectroencephalographyen_US
dc.subject.meshFemaleen_US
dc.subject.meshGestational Ageen_US
dc.subject.meshHumansen_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshInfant, Newborn, Diseases --diagnosisen_US
dc.subject.meshIntensive Care Units, Neonatalen_US
dc.subject.meshMagnetic Resonance Imagingen_US
dc.subject.meshMaleen_US
dc.subject.meshRisk Assessmenten_US
dc.subject.meshSeizures --diagnosisen_US
dc.subject.meshSensitivity and Specificityen_US
dc.subject.meshSeverity of Illness Indexen_US
dc.subject.meshSurvival Rateen_US
dc.subject.meshTomography, X-Ray Computeden_US
dc.titleClinico-etiological and EEG profile of neonatal seizures.en_US
dc.typeJournal Articleen_US
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