Safety and efficacy of dexamethasone implant along with phacoemulsification and intraocular lens implantation in children with juvenile idiopathic arthritis associated uveitis

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dc.contributor.authorJinagal, Jen_US
dc.contributor.authorGupta, Gen_US
dc.contributor.authorAgarwal, Aen_US
dc.contributor.authorAggarwal, Ken_US
dc.contributor.authorAkella, Men_US
dc.contributor.authorGupta, Ven_US
dc.contributor.authorSuri, Den_US
dc.contributor.authorGupta, Aen_US
dc.contributor.authorSingh, Sen_US
dc.contributor.authorRam, Jen_US
dc.date.accessioned2020-04-10T02:01:45Z
dc.date.available2020-04-10T02:01:45Z
dc.date.issued2019-01
dc.description.abstractPurpose: To assess the safety and efficacy of intraoperative intravitreal dexamethasone implant in patients of juvenile idiopathic arthritis (JIA)-associated uveitis undergoing phacoemulsification with posterior chamber intraocular lens (PCIOL) implantation. Methods: Retrospectively, data of patients with JIA-associated uveitis undergoing phacoemulsification with PCIOL implantation with intraoperative dexamethasone implant injection were analyzed. Patients with a minimum follow-up of 6 months were included. Primary outcome measures were ocular inflammation, intraocular pressure (IOP), best-corrected visual acuity (BCVA), and worsening of uveitis. Results: 8 eyes of 6 patients were included. BCVA was significantly improved at 1, 3, and 6 months postoperatively 0.20 ± 0.09, P = 0.008; 0.18 ± 0.11, P = 0.008; and 0.24 ± 0.11, P = 0.01, respectively. No statistical difference noted in mean IOP at various follow-up visits. None developed worsening of uveitis or Cystoid macular edema. Conclusion: Intraoperative intravitreal dexamethasone implant is a safe and effective in preventing and managing the postoperative inflammation in children with JIA-associated uveitic cataract.en_US
dc.identifier.affiliationsAdvanced Eye Centre, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, Indiaen_US
dc.identifier.affiliationsDepartment of Pediatrics, Division of Allergy and Immunology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, Indiaen_US
dc.identifier.citationJinagal J, Gupta G, Agarwal A, Aggarwal K, Akella M, Gupta V, Suri D, Gupta A, Singh S, Ram J. Safety and efficacy of dexamethasone implant along with phacoemulsification and intraocular lens implantation in children with juvenile idiopathic arthritis associated uveitis. Indian Journal of Ophthalmology. 2019 Jan; 67(1): 69-74en_US
dc.identifier.issn0301-4738
dc.identifier.issn1998-3689
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/197054
dc.languageenen_US
dc.publisherAll India Ophthalmological Societyen_US
dc.relation.issuenumber1en_US
dc.relation.volume67en_US
dc.source.urihttps://dx.doi.org/10.4103/ijo.IJO_713_18en_US
dc.subjectChildrenen_US
dc.subjectcataract surgeryen_US
dc.subjectdexamethasone implanten_US
dc.subjectJIAen_US
dc.subjectjuvenile idiopathic arthritisen_US
dc.subjectphacoemulsificationen_US
dc.subjectuveitisen_US
dc.titleSafety and efficacy of dexamethasone implant along with phacoemulsification and intraocular lens implantation in children with juvenile idiopathic arthritis associated uveitisen_US
dc.typeJournal Articleen_US
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