Inhibition of Heinz body induction in an in vitro model and total antioxidant activity of medicinal Thai plants.

Simple item page
dc.contributor.authorPalasuwan, Attakornen_US
dc.contributor.authorSoogarun, Suphanen_US
dc.contributor.authorLertlum, Tamapornen_US
dc.contributor.authorPradniwat, Paweenaen_US
dc.contributor.authorWiwanitkit, Virojen_US
dc.date.accessioned2009-05-27T17:35:39Z
dc.date.available2009-05-27T17:35:39Z
dc.date.issued2005-10-27en_US
dc.descriptionAsian Pacific Journal of Cancer Prevention.en_US
dc.description.abstractHerbs have been used for medicinal purposes for centuries and known to possess antioxidant properties that may help to reduce the risk of chronic diseases, cardiovascular disease, and cancer. We screen aqueous extracts from 20 medicinal plants in Thailand that were believed to possess anti-tumor activity, help immune-stimulating property and maintain blood stasis. The antioxidant activities were investigated in two bioassays. Firstly, we demonstrated inhibition of Heinz bodies induction caused by oxidants under in vitro condition. The percentages of Heinz body inhibition activity in plant extracts from Terminalia citrina, Cassia timoriensis, and Derris elliptica were the highest followed by Anamirta cocculus, and Oroxylum indicum respectively. In addition, we investigated total antioxidant activity in plant extracts by improved ABTS radical cation decolorization assay. The total antioxidant activity of the extract from Terminalia citrina was also the highest activity followed by Ficus pubigera, Derris elliptica, Anamirta cocculus, Caesalpinia sappan, and Oroxylum indicum respectively. Our results suggest medicinal Thai plants as valuable sources of antioxidants, which may have a potential anti-carcinogenic activity.en_US
dc.description.affiliationDepartment of Clinical Microscopy, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand. Attakorn.P@chula.ac.then_US
dc.identifier.citationPalasuwan A, Soogarun S, Lertlum T, Pradniwat P, Wiwanitkit V. Inhibition of Heinz body induction in an in vitro model and total antioxidant activity of medicinal Thai plants. Asian Pacific Journal of Cancer Prevention. 2005 Oct-Dec; 6(4): 458-63en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/37477
dc.language.isoengen_US
dc.source.urihttps://www.apocp.orgen_US
dc.subject.meshBenzothiazolesen_US
dc.subject.meshCell Culture Techniquesen_US
dc.subject.meshColorimetryen_US
dc.subject.meshDrugs, Chinese Herbal --pharmacologyen_US
dc.subject.meshHeinz Bodies --drug effectsen_US
dc.subject.meshHemoglobins --drug effectsen_US
dc.subject.meshHumansen_US
dc.subject.meshIndicators and Reagentsen_US
dc.subject.meshOxidation-Reduction --drug effectsen_US
dc.subject.meshPlant Componentsen_US
dc.subject.meshPlants, Medicinalen_US
dc.subject.meshSulfonic Acidsen_US
dc.subject.meshThailanden_US
dc.titleInhibition of Heinz body induction in an in vitro model and total antioxidant activity of medicinal Thai plants.en_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Asian Pacific Journal of Cancer Prevention