High Sensitivity C- Reactive Protein Level in Acute Cerebrovascular Accident (Stroke) at a Tertiary Care Centre.

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dc.contributor.authorBhaisare, Sunil Dhanrajen_US
dc.contributor.authorAniruddha Sunildatta Jogen_US
dc.contributor.authorAnuradha Krishnaraj Raoen_US
dc.contributor.authorHariom Uddhav Kolapkaren_US
dc.date.accessioned2020-11-18T10:18:06Z
dc.date.available2020-11-18T10:18:06Z
dc.date.issued2020-03
dc.description.abstractStroke is the leading cause of death worldwide and one of the main causes of long term disability. According to WHO, 15 million suffer from stroke each year. Studies have shown that levels of hsCRP measured shortly after stroke predicted complimentary aspects of prognosis. There is possibility that elevated hsCRP levels has direct relation to extent of cerebral tissue injury. We wanted to measure the levels of hsCRP in acute cerebrovascular accident. To correlate the level of hsCRP with severity of stroke and outcome.METHODSStudy was conducted in patients admitted in medical ward and medical ICU in tertiary care hospital (Grant Government Medical College and Sir JJ Group of Hospitals). It was a cross sectional study. A total of 150 patients who presented with stroke and fulfilled inclusion and exclusion criteria were enrolled in the study. In all patients hsCRP levels were measured within 48 hours of admission. Data was collected prospectively in a Microsoft Excel database. Statistical analysis was done using non-parametric ANOVA (Kruskal Wallis test) and Mann Whitney test.RESULTSMean age of patients was 59 ± 12 years. hsCRP levels were raised in stroke patients. Also values were found to be more in haemorrhagic stroke (value) than in ischemic stroke (value) and the difference was found to be significant. Significant correlation was also found between hsCRP levels and GCS with lower GCS scores associated with higher hsCRP levels in both types of stroke. Mean hsCRP level in survivors was 21.83 ± 23.17 mg/L and in non survivors was 82.07 ± 25.83 mg/L and the difference was statistically significant (p <0.0001)CONCLUSIONSWe concluded that hsCRP level is increased in cases of stroke (both ischemic and haemorrhagic) suggesting an inflammatory response in acute stroke. Increased levels of hsCRP correlated with severity of neurological deficit and worse outcome.en_US
dc.identifier.affiliationsDepartment of General Medicine, Grant Government Medial College and Sir JJ Group of Hospitals, Mumbai, Maharashtra, India.en_US
dc.identifier.affiliationsDepartment of General Medicine, Grant Government Medial College and Sir JJ Group of Hospitals, Mumbai, Maharashtra, India.en_US
dc.identifier.affiliationsDepartment of General Medicine, Grant Government Medial College and Sir JJ Group of Hospitals, Mumbai, Maharashtra, India.en_US
dc.identifier.affiliationsDepartment of General Medicine, Grant Government Medial College and Sir JJ Group of Hospitals, Mumbai, Maharashtra, India.en_US
dc.identifier.citationBhaisare Sunil Dhanraj, Aniruddha Sunildatta Jog, Anuradha Krishnaraj Rao, Hariom Uddhav Kolapkar. High Sensitivity C- Reactive Protein Level in Acute Cerebrovascular Accident (Stroke) at a Tertiary Care Centre.. Journal of Evolution of Medical and Dental Sciences. 2020 Mar; 9(10): 764-767en_US
dc.identifier.issn2278-4802
dc.identifier.issn2278-4748
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/214711
dc.languageenen_US
dc.publisherAkshantala Enterprises Private Limiteden_US
dc.relation.issuenumber9en_US
dc.relation.volume9en_US
dc.source.urihttps://dx.doi.org//10.14260/jemds/2020/166en_US
dc.subjecthsCRPen_US
dc.subjectIschemic Strokeen_US
dc.subjectHaemorrhagic Strokeen_US
dc.subjectPrognostic Marker in Strokeen_US
dc.titleHigh Sensitivity C- Reactive Protein Level in Acute Cerebrovascular Accident (Stroke) at a Tertiary Care Centre.en_US
dc.typeJournal Articleen_US
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