To Determine the Bacteriological Profile and Antibiotic Sensitivity Pattern of the Isolates Causing Ventilator Associated Pneumonia in ICU Patients

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dc.contributor.authorGarg, Nehaen_US
dc.date.accessioned2019-11-16T07:24:55Z
dc.date.available2019-11-16T07:24:55Z
dc.date.issued2018-01
dc.description.abstractBackground: Ventilator associated pneumonia (VAP) is a type of nosocomial pneumonia occurring in patients who are mechanically ventilated for more than 48 hours. VAP is the most common nosocomial infection occurring in the intensive care units and its incidence varies from 8% to 28%. AIMS & OBJECTIVES- This study was done to determine the bacteriological profile and antibiotic sensitivity pattern of the isolates obtained from the endotracheal aspirates of the clinically suspected patients of VAP in ICU.  Materials & Methods: Ventilator associated pneumonia (VAP) is a type of nosocomial pneumonia occurring in patients who are mechanically ventilated for more than 48 hours. VAP is the most common nosocomial infection occurring in the intensive care units and its incidence varies from 8% to 28%. AIMS & OBJECTIVES- This study was done to determine the bacteriological profile and antibiotic sensitivity pattern of the isolates obtained from the endotracheal aspirates of the clinically suspected patients of VAP in ICU. Results: Out of 110 patients included in the study, only 85 patients were diagnosed as VAP patients based on clinical and microbiological criteria. Pseudomonas aeruginosa (35.55%) was the most common gram-negative isolate obtained in VAP cases followed by Escherichia coli (27.77%) and Acinetobacter baumanni (16.66%). Among Gram positive bacteria, Staphylococcus aureus 40 (80%) was the most common isolate. The most active antibiotic against the gram-negative isolates was imipenem (82.2%), followed by piperacillin-tazobactum (77.7%) and amikacin (63.3%). All the Gram-positive isolates were susceptible to vancomycin and linezolid. Conclusion: Due to the increasing incidence of multi drug resistant pathogens in ICU, early and correct diagnosis of VAP is an important challenge for critical care physicians. Hence, knowing the bacteriological profile causing VAP and their routine antibiotic susceptibility pattern can improve the patient’s clinical outcome.en_US
dc.identifier.affiliationsAssistant Professor, Department of Microbiology, Heritage institute of Medical Sciences, Varanasi 221311, UP, India.en_US
dc.identifier.citationGarg Neha. To Determine the Bacteriological Profile and Antibiotic Sensitivity Pattern of the Isolates Causing Ventilator Associated Pneumonia in ICU Patients. International Archives of BioMedical and Clinical Research. 2018 Jan-Mar; 4(1): 68-71en_US
dc.identifier.issn2454-9894
dc.identifier.issn2454-9886
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/184244
dc.languageenen_US
dc.publisherIbn Sina Academy of Medieval Medicine & Sciencesen_US
dc.relation.issuenumber1en_US
dc.relation.volume4en_US
dc.source.urihttps://doi.org/10.21276/iabcr.2018.4.1.19en_US
dc.subjectVentilator associated pneumoniaen_US
dc.subjectIntensive care uniten_US
dc.subjectMulti drug resistanten_US
dc.subjectEndotrachealen_US
dc.titleTo Determine the Bacteriological Profile and Antibiotic Sensitivity Pattern of the Isolates Causing Ventilator Associated Pneumonia in ICU Patientsen_US
dc.typeJournal Articleen_US
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