Ultrasonic characterisation of malignant melanoma of choroid.

Simple item page
dc.contributor.authorJohn, Sen_US
dc.contributor.authorSujana, Hen_US
dc.contributor.authorSuresh, Sen_US
dc.contributor.authorSwarnamani, Sen_US
dc.contributor.authorBiswas, Jen_US
dc.contributor.authorGopal, Len_US
dc.date.accessioned1998-09-23en_US
dc.date.accessioned2009-05-29T08:35:26Z
dc.date.available1998-09-23en_US
dc.date.available2009-05-29T08:35:26Z
dc.date.issued1998-09-23en_US
dc.description.abstractAn in-vitro study of wave spectral analysis in 8 enucleated eyes was conducted in order to differentiate histological subtypes of malignant melanoma. To obtain the backscattering coefficient for the tissues, we used a broadband focussed transducer with a frequency range of 7-12 MHz and a centre frequency of 10 MHz. Experimental measurement of backscattering coefficient and attenuation coefficient at various frequencies was done by substitution techniques. The backscattering coefficient, scatterer size, and root mean square velocity fluctuation were derived by the numerical method, while the attenuation coefficient at 1 MHz was derived from attenuation coefficient at different frequencies. This study revealed that backscattering coefficient and attenuation coefficient, over a frequency range of 7-12 MHz, show an increase in the spindle cell type compared to the mixed cell type of malignant melanoma. Particularly, the scatterer size was significantly higher in the spindle cell group (p = 0.013) in contrast to the mixed cell type. Spindle cells have uniform and compact histological pattern which contributes to an increase in scatterer size and root mean square velocity fluctuation. The ultrasonically obtained parameters have been shown to have a good correlation with the histology of malignant melanoma.en_US
dc.description.affiliationMedical Research Foundation, Sankara Nethralaya, India.en_US
dc.identifier.citationJohn S, Sujana H, Suresh S, Swarnamani S, Biswas J, Gopal L. Ultrasonic characterisation of malignant melanoma of choroid. Indian Journal of Ophthalmology. 1998 Sep; 46(3): 153-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/70647
dc.language.isoengen_US
dc.source.urihttps://www.ijo.inen_US
dc.subject.meshChoroid Neoplasms --ultrasonographyen_US
dc.subject.meshHumansen_US
dc.subject.meshMathematicsen_US
dc.subject.meshMelanoma --ultrasonographyen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshUltrasonography --instrumentationen_US
dc.titleUltrasonic characterisation of malignant melanoma of choroid.en_US
dc.typeComparative Studyen_US
dc.typeIn Vitroen_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Ophthalmology