Sentinel lymph node biopsy versus complete axillary dissection in breast cancer: Oncological outcomes and lifestyle improvements – An Iraqi perspective

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dc.contributor.authorMahmood, ASen_US
dc.contributor.authorSfyyih, ANen_US
dc.contributor.authorAhmed, HAen_US
dc.contributor.authorHussein, RJen_US
dc.contributor.authorTurkey, FAen_US
dc.contributor.authorKamal, MSen_US
dc.contributor.authorAlhumaidi, AHen_US
dc.contributor.authorAl-Badri, Sen_US
dc.date.accessioned2025-06-18T11:56:19Z
dc.date.available2025-06-18T11:56:19Z
dc.date.issued2025-04
dc.description.abstractObjectives: To evaluate and compare the impact of ALND and SLNB on the oncological outcomes of BC patients. Materials and Methods: This is a prospective cohort study that included 160 patients with breast carcinoma who were scheduled to receive total axillary dissection. Patients were randomly assigned to undergo, together with breast surgery, either SLNB and ALND or SLNB followed by ALND only if the SLN was found positive. Follow-up included clinical examination every 4 months for the first 3 years, every 6 months for the following 2 years, and once a year thereafter. A mammography was scheduled annually. Results: After 6 months follow-up, eight types of complications were reported. In particular, lymphedema was reported in 4 women (5%) among sentinel LN group and 17 women (21.25%) in complete dissection group, with a highly significant difference. Collectively, 31 women (38.75%) among axillary dissection group had one or more complications compared with 17 women (21.25%) among sentinel LN group who had such complications with a significant difference. In multivariate analysis, each of older age (odds ratio [OR] = 2.62, 95% confidence interval [CI] = 1.24–10.86, P = 0.027), T2 tumor stage (OR = 11.3, 95% CI = 1.06–19.9, P = 0.044), and ALND (OR = 3.2, 95% CI = 1.12–5.31, P = 0.042) were significantly associated with increase the incidence of post-operative complications. Conclusion: SLNB is a highly efficient technique for evaluating the stage of the early BC. It is associated with less complication after surgery when compared to ALND. Increased post-operative complications in BC patients, whether handled with SLNB or ALND, are independently linked with advanced age and tumor stage.en_US
dc.identifier.affiliationsDepartment of Surgery, College of Medicine, University of Baghdad, Baghdad, Iraqen_US
dc.identifier.affiliationsDepartment of Surgery, Baghdad Medical City Hospital, Baghdad, Iraqen_US
dc.identifier.affiliationsDepartment of Surgery, Iraqi Board of Medical Specialization, Baghdad, Iraqen_US
dc.identifier.affiliationsDepartment of Surgery, Baghdad Teaching Hospital, Baghdad Medical City, Baghdad, Iraqen_US
dc.identifier.affiliationsDepartment of Surgery, Baghdad Teaching Hospital, Baghdad Medical City, Baghdad, Iraqen_US
dc.identifier.affiliationsDepartment of Surgery, Baghdad Medical City Hospital, Baghdad, Iraqen_US
dc.identifier.affiliationsDepartment of Surgery, Baghdad Teaching Hospital, Baghdad Medical City, Baghdad, Iraqen_US
dc.identifier.affiliationsDepartment of Surgery, College of Medicine, University of Baghdad, Baghdad, Iraq.en_US
dc.identifier.citationMahmood AS, Sfyyih AN, Ahmed HA, Hussein RJ, Turkey FA, Kamal MS, Alhumaidi AH, Al-Badri S. Sentinel lymph node biopsy versus complete axillary dissection in breast cancer: Oncological outcomes and lifestyle improvements – An Iraqi perspective. Indian Journal of Medical Sciences. 2025 Apr; 77(1): 18-23en_US
dc.identifier.issn1998-3654
dc.identifier.issn0019-5359
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/249718
dc.languageenen_US
dc.publisherScientific Scholaren_US
dc.relation.issuenumber1en_US
dc.relation.volume77en_US
dc.source.urihttps://dx.doi.org/10.25259/IJMS_260_2024en_US
dc.subjectsentinel lymph node biopsyen_US
dc.subjectAxillary lymph node dissectionen_US
dc.subjectBreast cancer oncological outcomesen_US
dc.subjectPost-operative complicationsen_US
dc.subjectIraqi breast cancer managementen_US
dc.titleSentinel lymph node biopsy versus complete axillary dissection in breast cancer: Oncological outcomes and lifestyle improvements – An Iraqi perspectiveen_US
dc.typeJournal Articleen_US
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