A rare case of duodenal carcinoid presenting as ectopic Cushing’s syndrome

Simple item page
dc.contributor.authorPugalendhi, Siddharthen_US
dc.contributor.authorDutta, Tarun Kumaren_US
dc.contributor.authorDhivyaen_US
dc.contributor.authorYadav, Kiranen_US
dc.date.accessioned2020-04-09T07:42:02Z
dc.date.available2020-04-09T07:42:02Z
dc.date.issued2019-05
dc.description.abstractACTH-dependent Cushing syndrome (CS) due to an ectopic source is responsible for approximately 10-15% cases of Cushing’s syndrome. It is associated with various tumors such as small cell lung cancer and well-differentiated bronchial or gastrointestinal neuroendocrine tumors. Many a times ectopic ACTH production is difficult to manage, and identification of the source may take many years. Hormonal diagnostics include assessments in basic conditions as well as dynamic tests, such as the high-dose dexamethasone suppression test and corticotrophin releasing hormone (CRH) stimulation test. Treatment selection depends on the type of tumor and its extent. In the case of neuroendocrine tumors, the main treatments are surgery and administration of somatostatin analogues or bilateral adrenalectomy in refractory cases and if the source remains unidentified. Here, we report a case who presented with features of Cushing’s syndrome which eventually through workup led us to a diagnosis of duodenal carcinoid producing ectopic ACTH which is extremely rare and was successfully treated.en_US
dc.identifier.affiliationsDepartment of General Medicine, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, Pondicherry, Indiaen_US
dc.identifier.citationPugalendhi Siddharth, Dutta Tarun Kumar, Dhivya, Yadav Kiran. A rare case of duodenal carcinoid presenting as ectopic Cushing’s syndrome. International Journal of Advances in Medicine. 2019 May; 6(3): 959-962en_US
dc.identifier.issn2349-3925
dc.identifier.issn2349-3933
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/194332
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber3en_US
dc.relation.volume6en_US
dc.source.urihttps://dx.doi.org/10.18203/2349-3933.ijam20192270en_US
dc.subjectACTH secreting Tumorsen_US
dc.subjectDuodenal carcinoiden_US
dc.subjectEctopic Cushing’s syndromeen_US
dc.titleA rare case of duodenal carcinoid presenting as ectopic Cushing’s syndromeen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ijam2019v6n3p959.pdf
Size:
237.88 KB
Format:
Adobe Portable Document Format
Download
Collections
International Journal of Advances in Medicine