Anthelminthic and Bactericidal Activity of Extracts from Flaveria trinervia Spring C. Mohr.
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Date
2011-10
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Abstract
Objective: To determine the anthelminthic and bactericidal activity of Flaveria trinervia.
Study design: Assessment of Anthelminthic and bactericidal activity.
Place and Duration of Study: Anthelminthic and bactericidal activity of extracts from
Flaveria trinervia Spring C. Mohr. between August 2010 and May 2011.
Methodology: The methanol and aqueous extracts of Flaveria trinervia were screened
for antibacterial activity against 20 clinical strains belonging to Pseudomonas
aeruginosa, Klebsiella pneumonia, Salmonella typhi, Salmonella paratyphi, Echerichia
coli, and Staphylococcus aureus isolated from different infectious sources. Minimum
inhibitory concentration (MIC) assay of both the extracts was carried out against clinical
isolates using two fold agar dilution method. Ciprofloxacin and piperazine citrate were
used as the standard reference for bactericidal and anthelminthic activity respectively.
Results: Evaluation of anti-bacterial activity revealed that both the extracts showed
effective activity against all the six bacterial pathogens. Specifically, aqueous extract
was more efficient than methanol extract but less potent than standard drug
ciprofloxacin. Among the various concentrations of aqueous extract tested, 250 mg/ml
showed efficient anthelminthic activity and among all the concentrations methanol
extract tested 250 mg/ml gave significant results. This investigation revealed that
methanol extract of F. trinervia showed significant anthelminthic activity against
Pheretima posthuma when compared to the aqueous extract.
Conclusion: From the results of this investigation we can conclude that F. trinervia is a
potent antibacterial and anthelminthic plant.
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Keywords
Flaveria trinervia, asteraceae, antibacterial activity;, anthelminthic activity, methanol extract, aqueous extract, minimum inhibitory concentration
Citation
Hoskeri H Joy, Krishna V. Anthelminthic and Bactericidal Activity of Extracts from Flaveria trinervia Spring C. Mohr. European Journal of Medicinal Plants. 2011 Oct-Dec; 1(4): 153-161.