Assessing the Impact of CHA2DS2-VASc Score on Oral Anticoagulation Recommendations for Non-valvular Atrial Fibrillation Patients in the Indian Population
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Date
2025-05
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Publisher
Indian Medical Association
Abstract
Background : Stroke is a major complication of Atrial Fibrillation (AF), often managed with oral anticoagulation to reduce associated morbidity and mortality. This study compares the CHADS2 and CHA2DS2-VASc scoring systems in guiding anticoagulation therapy in patients with Non-valvular Atrial Fibrillation (NVAF). Materials and Methods : A total of 87 NVAF patients from a Tertiary Care Center in Pune were evaluated using ECG and Echocardiography. CHADS2 and CHA2DS2-VASc scores were calculated and oral anticoagulation was initiated based on the CHA2DS2-VASc score. Follow-up was conducted at 3 and 6 months to assess compliance and bleeding events. Results : While CHADS2 recommended anticoagulation in 64% of patients, the CHA2DS2-VASc score increased this to 92%, reflecting a 28% higher identification rate. Eighty patients received oral anticoagulants. Discontinuation rates were 26% and 33% at 3 and 6 months, respectively. Minor bleeding was reported in 2.5% and 6% of patients at the same intervals. Conclusion : The CHA2DS2-VASc score offers more precise recommendations for anticoagulation in NVAF, identifying a higher number of patients at risk of Stroke compared to CHADS2.
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Keywords
CHA2DS2-VASc, CHADS2, Atrial Fibrillation, Stroke Prevention, Anticoagulation.
Citation
Pawar S, Janorkar S, Saner AA, Jadhav A, Gandhi MA, Deshmukh M, Arkar R.. Assessing the Impact of CHA2DS2-VASc Score on Oral Anticoagulation Recommendations for Non-valvular Atrial Fibrillation Patients in the Indian Population. Journal of The Indian Medical Association. 2025 May; 123(5): 47-52