Effects of preoperative dexmedetomidine on the occurrence of postoperative delirium in adult cardiac surgery patients

Simple item page
dc.contributor.authorMishra, S. C.en_US
dc.contributor.authorChowdhury, S.en_US
dc.date.accessioned2024-09-24T09:17:11Z
dc.date.available2024-09-24T09:17:11Z
dc.date.issued2023-06
dc.description.abstractBackground: Postoperative delirium (POD) is a serious complication in elderly patients undergoing cardiac surgery. This study was aimed at investigating the effect of perioperative administration of dexmedetomidine for general anesthesia maintenance on occurrence and duration of POD in elderly patients after cardiac surgery. Methods: This randomized control trial was done in central India after the institution's ethical committee gave their approval. One hundred and sixty-four patients were enrolled after cardiac surgery. Each patient gave their written consent after being fully informed. Patients over 60 years’ old who were going to have heart surgery were included in the study. Results: The difference in POD incidence between the dexmedetomidine and propofol groups was not statistically significant (p=0.0758). When compared to patients receiving propofol, patients receiving dexmedetomidine had a median delirium onset time that was delayed (second day vs. first day) and a shorter median delirium duration (2 days versus 3 days). Additionally, the patients receiving dexmedetomidine showed a lower VAS score and less use of opiate analgesics. Regarding other postoperative results, no difference was seen. Conclusions: Dexmedetomidine administration during cardiac surgery decreased the incidence, postponed the onset, and shorten the duration of POD in elderly patients.en_US
dc.identifier.affiliationsDepartment of Anesthesia, Sukh Sagar Medical College and Hospital, Jabalpur, Madhya Pradesh, Indiaen_US
dc.identifier.affiliationsDepartment of General Surgery, Pacific Institute of Medical Sciences, Udaipur, Rajasthan, Indiaen_US
dc.identifier.citationMishra S. C., Chowdhury S.. Effects of preoperative dexmedetomidine on the occurrence of postoperative delirium in adult cardiac surgery patients. International Journal of Research in Medical Sciences. 2023 Jun; 11(6): 2191-2195en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/233344
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber6en_US
dc.relation.volume11en_US
dc.source.urihttps://doi.org/10.18203/2320-6012.ijrms20231641en_US
dc.subjectDexmedetomidineen_US
dc.subjectPostoperative deliriumen_US
dc.subjectAnesthesiaen_US
dc.subjectCardiac surgeryen_US
dc.subjectElderly patientsen_US
dc.titleEffects of preoperative dexmedetomidine on the occurrence of postoperative delirium in adult cardiac surgery patientsen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
ijrms2023v11n6p2191.pdf
Size:
152.55 KB
Format:
Adobe Portable Document Format
Download
Collections
International Journal of Research in Medical Sciences